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rsbRD [2017-07-24 10:06:23]
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rsbRD [2017-07-24 10:06:23]

probably part of the stressosome, negative regulator of SigB activity
locus
BSU24760
pI
5.09
mw
31.66 kDa
protein length
278 aa Sequence Blast
gene length
834 bp Sequence Blast
function
control of SigB activity
product
RsbR paralog
essential
no
synonyms
yqhA
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.1|Sigma factors and their control] → [category|SW 3.4.1.2|Control of sigma factors]
  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.1|General stress proteins (controlled by SigB)]
  • [category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.6|Phosphorylation on a Thr residue]

    • Gene

    Coordinates
    2,562,966 → 2,563,802

    The protein

    Paralogous protein(s)

  • [protein|621357D1FB6AC1B0499732EFE226F982B26CE34E|RsbR], [protein|F53C527995909A1CFA72C7BF919DD10EE175C6D7|RsbRB], [protein|5EEEDE60CE9E5CDAEBAB0E03AABDF1DF62F1F002|RsbRC], [protein|6C5397BA5839E4DB25B370B39B6DA702147DA8B7|YtvA]

    • Modification

  • phosphorylation on Thr-181 by [protein|ADC52A22950736A0435AEEEC43F7407878786A81|RsbT] [Pubmed|21362065]

    • [SW|Localization]

  • cell membrane (according to Swiss-Prot)

    • Expression and Regulation

    Operons

    genes
    [gene|979D7A45EAD97C99015029400A85795061BAA367|rsbRD]
    description
    (according to [http://dbtbs.hgc.jp/COG/prom/yqhA.html DBTBS]) null

    sigma factors

  • [protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB]: sigma factor, [Pubmed|10482513], in [regulon|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB regulon]

    • regulation

  • expressed under stress conditions ([protein|search|SigB]) [Pubmed|10482513,20019076]
    • view in new tab

    Biological materials

    Mutant

  • MGNA-C475 (yqhA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2473 NBRP B. subtilis, Japan]

    • References

  • 15312768,10482513,20019076,17726680,17218307,11157946,28271471